Dir Opus is one of the very best file managers, imho.
I have found that you have to type in the serial,
*not* copy & paste.
Delete the key
HKEY_CLASSES_ROOT\CLSID\{0EB216EC-95B7-47ba-9CF7-3FB40616D5B5}
Re-enter serial.
Then go to > preferences/miscellaneous/internet settings ...and uncheck automatic update. Just to be safe, i also block it
with sygate.