LAME is better because it's updated - the Radium (hacked) codec is pretty old now and was based on the old professional Fraunhoffer version.
LAME 3.92 (exe, dll, CDex and winLame versions) is great for making MP3's.
As for JS/S, the general rule is to use JS for bitrates up to 160kBit/s then S after that. If you are encoding music that uses both stereo channels alot (classical or something), you should always use stereo.
Hope this helps