1. What is Systemec?
2. Put your Systemworks CD in your e:/drive, not any other one, and then try to run setup again.
3. Personally i would not be sad if I was unable to install Systemworks- rather the opposite.
4. Once you've paid to buy Systemworks you won't have to pay for such a support question. While not sure if they will care to reply, they will certainly not charge you for a second time for that!
5. You didn't really have to post this one three times to get an answer.