The program is probably updated, and the crack/serial are rendered useless. Well, I can only guess because you haven't told us.
Mail TSRh and tell them the problem. Make sure you describe any problems with the patch VERY CLEARLY and be polite. These guys are very busy, but they'll help you out if they can.
P.S. Download any trial or whatever at the same time you mail them, just to be sure you're both working with the same version.